FDA approved new treatment for adults with relapsed or refractory large-B-Cell lymphoma
On Feb. 5, 2021, the FDA approved Breyanzi (lisocabtagene maraleucel), a cell-based gene therapy to treat adult patients…
Researchers used patients’ cells to test gene therapy for rare eye disease
On Jan. 28, 2021, scientists at the National Eye Institute (NEI) have developed a promising gene therapy strategy…
Ultragenyx announced plans to build large-scale gene therapy manufacturing facility for rare diseases
On Nov. 9, 2020, Ultragenyx announced that it planned to build a new large-scale gene therapy manufacturing facility…
Scientists used gene therapy and a novel light-sensing protein to restore vision in mice
On Oct. 22, 2020, a newly developed light-sensing protein called the MCO1 opsin restored vision in blind mice…
Catalent signed agreement with AstraZeneca to expand manufacturing support for COVID-19 vaccine AZD1222
On Aug. 24, 2020, Catalent announced that it had contracted to provide drug substance manufacturing to AstraZeneca for…
Penn Medicine developed gene therapy to treat Duchenne muscular dystrophy (DMD
On Oct. 7, 2019, Penn Medicine announced it had developed gene therapy to treat Duchenne muscular dystrophy (DMD)…
St. Jude announced a cure for SCID-X1, commonly known as bubble boy disease
On Apr. 18, 2019, St. Jude announced a cure for SCID-X1, commonly known as bubble boy disease. By…
FDA approval brought first gene therapy to the U.S.
On Aug. 30, 2017, the U.S. Food and Drug Administration (FDA) approved Kymriah (tisagenlecleucel) for certain pediatric and…
OHSU announced creation of new embryonic stem cell and gene therapy center
On Mar. 5, 2014, Oregon Health & Science University (OHSU) announced the creation of the Center for Embryonic…
BioLife Solutions was incorporated in Seattle
On Aug. 24, 2007, BioLife Solutions was incorporated in Seattle. BioLife Solutions (formerly Cryomedical Sciences) is a class-defining…
UI Microbiology Professor Mark Stinski made the discoveries of CMV promoter and was named Iowa Inventor of the Year
On Sept. 30, 2003, University of Iowa (UI) Microbiology Professor Mark Stinski made the discoveries of CMV promoter…
China granted the world’s first regulatory approval of a gene therapy product
In 2003, China granted the world’s first regulatory approval of a gene therapy product, Gendicine (Shenzhen SiBiono GenTech),…
First gene therapy trial for patients with Hunter syndrome began at the University of Minnesota
On Oct. 25, 1996, the first gene therapy trial for patients with Hunter syndrome was begun at the…
Targeted Genetics began human clinical testing using gene therapy to combat HIV infection
In 1993, Targeted Genetics, a subsidiary of the Immunex Corporation, became the first company to begin human clinical…
University of Iowa Research Foundation received U.S. patents for CMV promoter
In 1992, the University of Iowa (UI) Research Foundation received its first U.S. patent on the CMV promoter,…
The first human gene therapy to treat cancer was started
On Jan. 29, 1991, the first human gene therapy to treat cancer was started at the National Cancer…
First human gene therapy trial was conducted
On Sept. 14, 1990, a four-year old girl, Ashanti DeSilva, became the first gene therapy patient. She had…
Dr. Steven A Rosenberg conducted the first human gene transfer trial
On May 22, 1989, Dr. Steven A. Rosenberg and his team at the National Cancer Institute (NCI) performed…
H. Stewart Parker founded Targeted Genetics Corp. in Seattle
In 1989, H. Stewart Parker became CEO of Targeted Genetics, an Immunex Corp. spin-off in Seattle. which specialized…
The O’Neal Comprehensive Cancer Center at University of Alabama was founded
In 1971, the University of Alabama at Birmingham Comprehensive Cancer Center (UAB) was founded and received its NCI…