CIRM invested $10 million to build California Cell and Gene Therapy Manufacturing Network
On May 31, 2023, the California Institute for Regenerative Medicine (CIRM) awarded $10 million to five facilities as…
FDA approved first topical gene therapy for treatment of wounds in patients with dystrophic epidermolysis bullosa
On May 19, 2023, the U.S. Food and Drug Administration (FDA) approved Krystal Biotech’s Vyjuvek, a herpes-simplex virus…
Gene therapy allowed teen to see snowflakes for the first time
On Apr. 5, 2023, researchers at Oregon Health & Science University’s OHSU Casey Eye Institute announced that gene…
Biotechnology | CRISPR | Disease | Prehistory | Therapeutics
2.6 billion-year-old ancestors of the CRISPR gene-editing tool resurrected
On Jan. 4, 2023, an international research group announced it had for the first time reconstructed ancestors dating…
FDA approved first gene therapy for treatment of high-risk, non-muscle-invasive bladder cancer
On Dec. 16, 2022, the U.S. Food and Drug Administration approved Ferring Pharmaceuticals’ Adstiladrin (nadofaragene firadenovec-vncg), a non-replicating…
FDA approved first gene therapy to treat adults with Hemophilia B
On Nov. 22, 2022, the U.S. Food and Drug Administration approved the investigational gene therapy etranacogene dezaparvovec or…
First gene therapy for adults with severe hemophilia A, BioMarin’s ROCTAVIAN, approved by EC
On Aug. 24, 2022, BioMarin Pharmaceutical announced that the European Commission (EC) had granted conditional marketing authorization (CMA)…
FDA approved first cellbBased gene therapy to treat adult and pediatric patients with Beta-thalassemia
On Aug. 17, 2022, the U.S. Food and Drug Administration approved Zynteglo (betibeglogene autotemcel) developed by bluebird bio,…
Athenex and Center for Cell and Gene Therapy announced allowance of first U.S. patent around CAR-NKT cell therapy
On Oct. 18, 2021, Athenex and the Center for Cell and Gene Therapy at Baylor College of Medicine,…
Spacestation astronauts successfully demonstrated DNA repair in space using CRISPR technology
On Aug. 27, 2021, National Aeronautics and Space Administration (NASA) Space station astronauts successfully demonstrated DNA repair in…
Gene therapy restored immune function in children with rare immunodeficiency
On May 10, 2021, the National Institutes of Health reported that an investigational gene therapy can safely restore…
FDA approved first cell-based gene therapy for adult patients with multiple myeloma
On Mar. 27, 2021, the FDA approved Abecma (idecabtagene vicleucel), a cell-based gene therapy to treat adult patients…
Novartis and Gates Foundation collaborate to discover and develop in vivo gene therapy for sickle cell disease
On Feb. 17, 2021, Novartis announced that it had entered into a grant agreement with the Bill &…
FDA approved new treatment for adults with relapsed or refractory large-B-Cell lymphoma
On Feb. 5, 2021, the FDA approved Breyanzi (lisocabtagene maraleucel), a cell-based gene therapy to treat adult patients…
Researchers used patients’ cells to test gene therapy for rare eye disease
On Jan. 28, 2021, scientists at the National Eye Institute (NEI) have developed a promising gene therapy strategy…
Ultragenyx announced plans to build large-scale gene therapy manufacturing facility for rare diseases
On Nov. 9, 2020, Ultragenyx announced that it planned to build a new large-scale gene therapy manufacturing facility…
Scientists used gene therapy and a novel light-sensing protein to restore vision in mice
On Oct. 22, 2020, a newly developed light-sensing protein called the MCO1 opsin restored vision in blind mice…
Catalent signed agreement with AstraZeneca to expand manufacturing support for COVID-19 vaccine AZD1222
On Aug. 24, 2020, Catalent announced that it had contracted to provide drug substance manufacturing to AstraZeneca for…
Penn Medicine developed gene therapy to treat Duchenne muscular dystrophy (DMD
On Oct. 7, 2019, Penn Medicine announced it had developed gene therapy to treat Duchenne muscular dystrophy (DMD)…
St. Jude announced a cure for SCID-X1, commonly known as bubble boy disease
On Apr. 18, 2019, St. Jude announced a cure for SCID-X1, commonly known as bubble boy disease. By…
Biotechnology | Cloning | CRISPR | Disease | Genomics | Medicine | Therapeutics
Moratorium on heritable genome editing published in “Nature”
On Mar. 13, 2019, Nature published a call for a global moratorium on heritable human genome editing signed by…
Biotechnology | Diagnostics | Genomics | Medicine | Non-Profit Research | Ophthalmogy | Stem Cell | Therapeutics
Wold Foundation of Wyoming announced a gift of $2.5 million to help in OHSU’s fight against macular degeneration
On Jun. 7, 2018, the Wold Foundation of Wyoming announced a gift of $2.5 million to help in…
FDA approval brought first gene therapy to the U.S.
On Aug. 30, 2017, the U.S. Food and Drug Administration (FDA) approved Kymriah (tisagenlecleucel) for certain pediatric and…
OHSU announced creation of new embryonic stem cell and gene therapy center
On Mar. 5, 2014, Oregon Health & Science University (OHSU) announced the creation of the Center for Embryonic…
BioLife Solutions was incorporated in Seattle
On Aug. 24, 2007, BioLife Solutions was incorporated in Seattle. BioLife Solutions (formerly Cryomedical Sciences) is a class-defining…
UI Microbiology Professor Mark Stinski made the discoveries of CMV promoter and was named Iowa Inventor of the Year
On Sept. 30, 2003, University of Iowa (UI) Microbiology Professor Mark Stinski made the discoveries of CMV promoter…
China granted the world’s first regulatory approval of a gene therapy product
In 2003, China granted the world’s first regulatory approval of a gene therapy product, Gendicine (Shenzhen SiBiono GenTech),…
Biotechnology | Genomics | HIV | Oncology
Stanford researchers became the first to use RNAi to switch off genes in mice
In 2002, Stanford geneticist Mark Kay uses a gene-therapy technique known as RNA inhibition to switch off genes…
OHSU researchers produced the first genetically modified monkey
On Jan. 11, 2001, Oregon Health Sciences University (OHSU) researchers reported the production of the world’s first genetically…
First gene therapy trial for patients with Hunter syndrome began at the University of Minnesota
On Oct. 25, 1996, the first gene therapy trial for patients with Hunter syndrome was begun at the…