On Oct. 29, 2020, Mammoth Biosciences announced that it had signed agreements with MilliporeSigma and Hamilton Company targeting commercialization of a high-throughput CRISPR-based SARS CoV-2 test. The test leverages Mammoth’s DETECTR BOOST platform and will provide a sample-to-answer turnkey solution for commercial laboratories to enable a multi-fold increase in testing capacity.

The high-throughput systems will be compatible with both nasal swab and saliva samples and are targeting 1500 tests per 8-hour shift with minimal user interaction. Mammoth Biosciences plans to submit the assay for FDA Emergency Use Authorization later this year.

Mammoth’s DETECTR BOOST™ SARS-CoV-2 assay reagent kits, which will be contract manufactured by MilliporeSigma, rival PCR in sensitivity while being less prone to supply chain risk. The testing system will also leverage standard, automated liquid handling equipment such as those from Hamilton Company to enable rapid processing of patient samples. By implementing this unique offering, CLIA laboratories will be able to significantly improve their capacity to regularly test communities and businesses in need.