On Sept. 21, 2022, during United Nations General Assembly week, the Bill & Melinda Gates Foundation—alongside governments, philanthropies, the private sector, NGOs, and global and community leaders—announced commitments totaling $1.27B to improve and save millions of lives.

The funding will address overlapping global crises that have reversed the progress already made toward achieving the UN Sustainable Development Goals (Global Goals). The foundation’s sixth annual Goalkeepers Report notes that nearly every indicator of the Global Goals is off track at the halfway point for achieving them by 2030. Despite these challenges, the report highlights opportunities to accelerate progress by investing in long-term solutions and innovative approaches to entrenched issues, including poverty, inequality, and climate change.

The Goalkeepers event convened global leaders and changemakers to discuss current and future efforts to achieve the Global Goals. Mia Mottley, Prime Minister of Barbados; Pedro Sanchez, Prime Minister of Spain; Bill Gates; Melinda French Gates; more than 300 young changemakers; and other emerging and established leaders from around the world participated in the event.

Also, at the Global Fund Replenishment Conference, governments and the private sector joined together to pledge a record-high level of commitment that will advance the goal of achieving good health and well-being for all. The funding will go toward the Global Fund’s goal of saving 20 million more lives from HIV, TB, and malaria; building more resilient health systems to prevent future pandemics; and putting the world back on track to end these diseases by 2030. This pledge includes the foundation’s largest commitment yet to the Global Fund of $912 million.