In 1960, National Institute of Health grants allow the Medical Research Foundation of Oregon to acquire property and begin construction of Oregon Regional Primate Research Center (ORPRC).

Designated the Oregon National Primate Research Center (ONPRC) in 2002, the center conducts basic and applied biomedical research in three fields: Division of Reproductive Sciences, Division of Neuroscience, and the Division of Pathobiology and Immunology. As one of eight national primate centers, ORPRC is a resource, both local and international, for scientists and academic and research institutions.