On Feb. 12, 2007, a study published in the Journal of Medicinal Chemistry by researchers led by Dr. Lakshmi Kotra, a molecular and cell specialist at the Toronto Research Institute, announced they had discovered a new anti-malaria agent, KP-15.

According to the study results, after penetrating into ODCase (Orotidine monophosphate decarboxylase) – an enzyme that is very important for the survival and regeneration of parasites – KP-15 inhibited the activity of this enzyme, thereby destroying the worm.