On Apr. 13, 2022, the U.S. Food and Drug Administration announced that the legislation clarifying the agency can regulate tobacco products containing nicotine from any source took effect Apr. 14, 2022.

To-date, manufacturers, distributors, importers and retailers of products containing non-tobacco nicotineﾗthat is, nicotine not made or derived from tobacco, such as synthetic nicotineﾗmust ensure compliance with applicable requirements under the FD&C Act.