Resverlogix clinical candidate apabetalone featured as potential COVID-19 treatment in publication
On Mar. 24, 2020, Resverlogix announced a Mar. 23, 2020 bioRxiv publication that has shown apabetalone to inhibit specialized proteins ヨ called bromodomain and extraterminal domain (BET) proteins ヨ from interacting with a SARS-CoV-2 viral protein, with potential for limiting viral reproduction in human cells.
The article titled: モA SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposingヤ by Gordon et al, identified BRD2/4 as a binding partner of viral protein E. Apabetalone was shown to disrupt this interaction.
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Source: Resverlogix Corp.
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