On Aug 10, 2007, the U.S. Centers for Disease Control and Prevention (CDC) notified MMWR readers of revised recommendations to vaccinate all persons ages 11-18 with MCV4 at earliest opportunity.

ACIP continued to recommend routine vaccination for persons aged 19–55 years who are at increased risk for meningococcal disease: college freshmen living in dormitories, microbiologists routinely exposed to isolates of Neisseria meningitidis, military recruits, travelers to or residents of countries in which N. meningitidis meningitis is hyperendemic or epidemic, persons with terminal complement component deficiencies, and persons with anatomic or functional asplenia.