The first genetically engineered mouse model showing amyloid plaques was developed at the University of Minnesota

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In 1996, the first genetically engineered mouse model showing amyloid plaques and dysfunctional learning and memory found in Alzheimer’s disease developed by a research team led by neurobiologist Karen Hsiao at the University of Minnesota.

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Source: University of Minnesota
Credit: Photo: Courtesy University of Minnesota , Departments of Neurology and Neuroscience.