In 1971, John Vane discovered how aspirin worked, a finding that a daily low dose of aspirin prevents heart attacks and strokes, saving millions of lives each year, and the development of angiotensin converting enzyme (ACE) inhibitors for the treatment of hypertension. In 1982 he won a Nobel prize for medicine or physiology for discovering how aspirin works�sharing it with Sune Bergstr�m and Bengt Samuelsson of Sweden.