On Nov. 6, 1918, following improved influenza case numbers, the Kentucky Board of Health lifted the closure order and gathering ban on Louisville.

Churches reopened Nov. 10, the first time the pews were occupied for regular service in five weeks. To prepare for the complete reopening of the city and to help stave off a return of the epidemic, the Louisville Boards of Health and Public Safety issued a set of regulations to prevent crowding. All stores were to be fully ventilated at all times and kept at a proper temperature.