In 1991, the University of Michigan Rogel Cancer Center received National Cancer Institute (NCI) comprehensive center designation. The Rogel Cancer Center has a distinguished history of scientific excellence, collaboration, and impact in basic science, clinical research, and cancer control research.

With a focus on team science and research excellence, Rogel Cancer Center members harness innovation by engaging disciplines not typically associated with cancer advances. This includes faculty in fields such as engineering and mathematics, as well as more traditional collaborations among faculty in the schools of medicine, public health, pharmacy, nursing, and social work.

Research at the Rogel Cancer Center is divided into seven programs: cancer biology, cancer genetics, cancer hematopoiesis and immunology, developmental therapeutics, translational and clinical research, cancer epidemiology, and health behavior and outcomes.