On Aug. 27, 2025, the U.S. Centers for Disease Control and Prevention (CDC) Director Susan Monarez has left the agency less than a month after being sworn in, the Department of Health and Human Services confirmed, and three senior officials have resigned.

CDC Chief Medical Officer Debra Houry and National Center for Immunization and Respiratory Diseases Director Demetre Daskalakis are also out after resigning, Houry told Reuters.

National Center for Emerging and Zoonotic Infectious Diseases Director Daniel Jernigan has also resigned, days after the agency reported the first U.S. human case of screwworm linked to an ongoing outbreak in Central America.

Reuters has reviewed their resignation letters.

“I am not able to serve in this role any longer because of the ongoing weaponizing of public health,” Daskalakis wrote in his letter. The Washington Post first reported Monarez was being ousted earlier on Wednesday, citing multiple Trump administration officials familiar with the matter.

“Susan Monarez is no longer director of the Centers for Disease Control and Prevention. We thank her for her dedicated service to the American people,” a posting on the department’s official X account said.

Monarez, a federal government scientist, was confirmed by the U.S. Senate on July 29 to lead the CDC after President Donald Trump nominated her earlier in the year. She was sworn in by HHS Secretary Robert F. Kennedy Jr. on July 31.