In 1989, Oregon Bioscience Association (OBA) was established as the Bioforum Foundation by a consortium of universities, public officials, educators and bioscience executives.

The organization became the Oregon Biotechnology Association in 1990, and started doing business as the Oregon Bioscience Association in 2000 (Oregon Bio). Today Oregon Bio supports the regional bioscience community through networking, educational programs, enterprise support, advocacy, and the enhancement of research collaboration.