On Feb. 6, 2024, Oregon Health & Science University (OHSU) announced research that revealed as much as a four-fold increase in immune response when people alternate from one arm to the other when given a multi-dose vaccine.

The laboratory study led by researchers at OHSU measured the antibody response in the blood of 947 people who received two-dose vaccinations against COVID-19 early in the pandemic. The study was published in The Journal of Clinical Investigation.