Single-cell study of Ebola highlighted virus’s lethal maneuvers

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On Nov. 6, 2020, in a study published in Cell, the researchers identified antiviral defense genes that the virus suppresses, and other genes the virus activates to potentially boost its replication in cells.

The scientists, from the Broad Institute of MIT and Harvard, MIT, the National Institutes of Health (NIH), Stanford University, and other institutions described how they sampled roughly 100,000 single immune cells from Ebola-infected rhesus monkeys at various stages of disease, and studied gene expression and protein activity in each of these cells individually.

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Source: Broad Institute
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