On Sept. 22, 2025, the U.S. Department of Agriculture (USDA) reported that over 400,000 turkeys have been euthanized in South Dakota because of bird flu in the past month.

With the most recent detection coming a week ago, the state continues to lead the nation in affected birds by a wide margin.

In total, about 420,000 birds have been killed in the state in the last 30 days to mitigate spreading of the disease. According to the USDA’s Animal and Plant Health Inspection Service, that’s across eight commercial turkey farms and one backyard flock.

Specifically, the USDA reports there are detections across the eastern part of South Dakota in Beadle, McPherson, Jerauld, Spink and Faulk counties.

North Dakota is also facing outbreaks resulting in over 100,000 birds dead. Minnesota is reporting its first detection in the past month as well.