On Jan. 30, 2026, Eli Lilly announced plans to invest more than $3.5 billion in a new manufacturing facility in the Lehigh Valley, Pennsylvania. The site will serve as Lilly’s newest injectable medicine and device manufacturing facility that will produce next-generation weight-loss therapies, including retatrutide, a first-in-class investigational GIP, GLP-1 and glucagon triple hormone receptor agonist.

This is the fourth new U.S. manufacturing site Lilly has announced since February 2025, as part of its commitment to bolster domestic medicine production.  

Lilly will bring 850 high-value jobs to the area, including engineers, scientists, operations personnel and lab technicians. Construction, expected to begin in 2026, is anticipated to generate 2,000 construction jobs. The site will be operational in 2031.

The Lehigh Valley site, located in Fogelsville, Pennsylvania, was selected from more than 300 applications, partly based on its proximity to STEM universities, its technical manufacturing economy, and its existing infrastructure. In addition, with increasing demand from the biotech industry, the region offers convenient access to utilities, transportation, and favorable zoning and incentives.

Lilly will utilize advanced technologies, including AI, machine learning, integrated monitoring, and data analytics, to enable efficient operations and a reliable supply of medicine. The company will partner with local universities and invest in education across Pennsylvania to develop talent.