On Nov. 1, 2022, study results published in JAMA found that estimates in this cross-sectional study of 694,660 mean deaths per year between 2015 and 2019 suggested that excessive alcohol consumption accounted for 12.9% of total deaths among adults aged 20 to 64 years and 20.3% of deaths among adults aged 20 to 49 years.

Among adults aged 20 to 64 years, the proportion of alcohol-attributable deaths to total deaths varied by state.