On Feb. 12, 2024, the U.S. Centers for Disease Control and Prevention (CDC) announced that Cambodia had reported four recent human infections with highly pathogenic avian influenza (HPAI) A(H5N1) (bird flu) virus. These are the first human infections with HPAI A(H5N1) virus identified in Cambodia in 2024.

Six sporadic human infections with HPAI A(H5N1) bird flu virus occurred in Cambodia in February, October, and November of 2023.