On Apr. 16, 2020, the International Vaccine Institute (IVI) announced that the Coalition for Epidemic Preparedness Innovations (CEPI) had granted $6.9 million funding to INOVIO to work with IVI and the Korea National Institute of Health (KNIH) for a Phase 1/2 clinical trial of INOVIO’s COVID-19 vaccine candidate (INO-4800) in South Korea. IVI conducted the trial in parallel to INOVIO’s Phase 1 INO-4800 study underway in the U.S. since April 6, 2020 with 40 healthy adults receiving the vaccine candidate and eventually expanding to older adults.

NOVIO’s DNA vaccine platform is also utilized in their MERS vaccine, INO-4700, for which IVI previously conducted Phase I clinical testing with GeneOne Life Science in South Korea.

This news follows the announcement from the Korean Ministry of Food and Drug Safety made on April 13^th that they will adopt a fast-track approval process for COVID-19 vaccine and treatment clinical trials. The period of clinical trial screening will be shortened to seven days (down from 30 days) for substances with experience in use and within 15 days for new materials. Additionally, vaccines developed with a proven safety platform, such as INOVIO’s DNA platform, will be exempt from toxicology tests which will minimize data submission and expedite clinical trials. Plumbline Life Sciences (XKRX: 222670) of South Korea also collaborated on this project. Korea Centers for Disease Control and Prevention (KCDC) and the KNIH and has also pledged their support for IVI’s testing efforts.