On Jun. 5, 2018, a new flagship cancer center was established as the Fred & Pamela Buffett Cancer Center, part of the Nebraska Medicine Cancer Network and the University of Nebraska Medical Center (UNMC).

The Buffett Cancer Center, opened in 2017 and consists of a 10-story cancer research tower and 8-story inpatient hospital and outpatient center that includes medical, surgical and radiation oncology clinics, a 24/7 infusion center, radiology, lab services, radiation therapy and surgical services.