On Mar. 26, 2005, The University of Southern California/Norris Comprehensive Cancer Center in Los Angeles announced a $15 million gift from local philanthropist Henrietta C. Lee to recruit new faculty and support research on the treatment and prevention of cancer in women.

In 1998, Harold and Henrietta Lee gave $5 million gift that made it possible to create endowed chairs and establish the Harold E. and Henrietta C. Lee Breast Center at the the USC Norris Comprehensive Cancer Center.

In 1973, the USC Norris Comprehensive Cancer Center was designated a National Cancer Institute Comprehensive Cancer Center, one of the first eight comprehensive cancer centers.