WHO reports increased incidence of Sudan virus disease in Uganda

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On Mar. 8, 2025, the World Health Organization (WHO) announced that since the outbreak of Sudan virus disease (SVD) was declared in Uganda on January 30, 2025, a total of 14 cases (including 12 confirmed cases and two probable cases) including four deaths (two confirmed and two probable) have been

Sudan virus disease is a severe disease, belonging to the same family as Ebola virus disease. It is caused by Sudan virus (SUDV) and can result in high case fatality. It is typically characterized by acute onset of fever with non-specific symptoms/signs (e.g., abdominal pain, anorexia, fatigue, malaise, myalgia, sore throat) usually followed several days later by nausea, vomiting, diarrhoea, and occasionally a variable rash.reported.

As of March 5, 2025, 192 new contacts have been identified and are under follow-up in Kampala, Ntoroko and Wakiso. In the absence of licensed vaccines and therapeutics for the prevention and treatment of SVD, the risk of potential serious public health impact is high.

The Ministry of Health (MoH) has activated the coordination structures at national and subnational levels, including the Incident Management Team and dispatched Rapid Response Teams to the affected districts. Regional Emergency Operation Centers have been activated in Fort Portal, Ntoroko, Kampala, and Mbale districts.

Sudan virus disease (SVD) is a severe, often fatal illness affecting humans. Sudan virus (SUDV) was first identified in southern Sudan in June 1976. Since then, the virus has emerged periodically and up to now and prior to this current one, eight outbreaks caused by SUDV have been reported, five in Uganda and three in Sudan. The case fatality rates of SVD have varied from 41% to 70% in past outbreaks.

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Source: World Health Organization
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