On Apr. 28, 2022, the Ministry of Health of the Democratic Republic of the Congo declared an outbreak of Ebola virus disease (EVD) in the country after a case was confirmed from Mbandaka, Equateur province. The onset of symptoms was on 5 April.

The case subsequently died on 21 Apr. , and a safe and dignified burial was performed. The second case, a family member, was confirmed on 25 April. As of 27 April, 267 contacts have been identified; other measures, including contact tracing, further investigations, decontamination of households and health facilities, were ongoing.