On Jan. 25, 2024, dozens of noted scientists, philanthropists, and Washington University, state and local leaders celebrated the dedication of one of the worldﾒs largest neuroscience research buildings, a gleaming state-of-the-art facility on the Washington University Medical Campus. The naming of the building followed a gift from James and Elizabeth McDonnell.

The university invested $616 million to construct the building and broke ground in March 2020, just as the COVID-19 pandemic took hold. It sits at 4370 Duncan Ave., on the eastern edge of the Medical Campus.