On Mar. 6, 2022, the U.S. Department of Agricultureﾒs Animal and Plant Health Inspection Service confirmed the presence of highly pathogenic avian influenza (HPAI) in a commercial mixed species flock in Charles Mix County, South Dakota.

Samples from the flock were tested at the South Dakota State University Animal Disease Research and Diagnostic Laboratory, part of the National Animal Health Laboratory Network, and confirmed at the APHIS National Veterinary Services Laboratories (NVSL) in Ames, Iowa.