On Mar. 24, 2023, the U.S. Centers for Disease Control and Prevention (CDC) announced that Tuberculosis (TB) in the U.S. increased slightly during 2022 although it remained lower than prepandemic years. Reported TB decreased gradually in the U.S. during 1993-2019, reaching 2.7 cases per 100,000 persons in 2019. Incidence substantially declined in 2020 to 2.2, coinciding with the COVID-19 pandemic.

During 2022, reported TB incidence increased slightly. Among non–U.S.-born persons with TB, the proportion who had recently arrived in the United States increased. Higher TB incidence among American Indian or Alaska Native and Native Hawaiian or other Pacific Islander persons compared with other race and ethnicity groups represents an ongoing health disparity.

TB incidence is returning to prepandemic levels. TB diagnosis and treatment to interrupt transmission and prevention of TB through treatment of latent TB infection are critical to U.S. TB elimination efforts.