On Apr. 2, 2003, the Virginia Mason Research Center, located in Seattle, was renamed Benaroya Research Institute at Virginia Mason (BRI) in recognition of the Benaroya family of Seattle.

The BRI is focused on molecular and cellular biology of the human immune system and on genetics of human diseases. BRI has a clinical research program that supports more than 150 studies each year, primarily Phase II-III medication and device trials, in 25 different subspecialty areas.