In 1976, the Ohio State University Cancer Center (OSUCCC) received National Cancer Institute (NCI) comprehensive center designation. The patient care arm of the OSUCCC is the Arthur G. James Cancer Hospital and Richard J. Solove Research Institute. The center is now  known as the OSUCCC – James.

The OSUCCC is one of only a few centers funded by the NCI to conduct both phase I and phase II clinical trials on novel anticancer agents provided by the NCI.