In 1850, the Female Medical College of Pennsylvania, later known as the Woman’s Medical College of Pennsylvania was founded, becoming the second medical institution in the world established to train women in medicine to earn the M.D. degree.

In 1970, the college admitted, and was renamed as the Medical College of Pennsylvania. In 1993, the college and hospital merged with Hahnemann Medical School. In 2003, the colleges were absorbed by Drexel University College of Medicine.