Biotechnology | Genomics | HIV | Oncology
Stanford researchers became the first to use RNAi to switch off genes in mice
In 2002, Stanford geneticist Mark Kay uses a gene-therapy technique known as RNA inhibition to switch off genes…
Stanford researchers solved the structure of the RNA polymerase protein
On Apr. 24, 2000, Stanford researchers announced they have solved the structure of the RNA polymerase protein, one…
Biotechnology | CDC | Diagnostics | HIV | Therapeutics
The CDC expanded the HIV definition to include any detectable viral load assay
On Apr. 1, 2000, the Centers for Disease Control and Prevention (CDC) announced that it had expanded the…
Ribozyme Pharmaceuticals announced IPO
On Apr. 12, 1996, Ribozyme Pharmaceuticals announced an initial public offering of 2,000,000 shares of its Common Stock…
Amgen acquired Boulder-based Synergen facility
In 1994, Amgen announced it had acquired Boulder-based Synergen for a $239.6-million or $9.25 per share. Synergen was…
Co-discovery of microRNAs
In 1993, Harvard Medical School Genetics researcher Gary Ruvkun co-discovered small regulatory RNAs (microRNAs), which led to RNA…
Drs. Joan and Ron Conaway at the OMRF discovered Elongin a genetic transcription factor
In 1993, Drs. Joan and Ron Conaway from the Oklahoma Medical Research Foundation (OMRF) discovered Elongin A (EloA)…
Thomas R. Cech was awarded Nobel Laureate in Chemistry
In 1989, Thomas Cech from the University of Colorado in Boulder was awarded the 1989 Nobel Prize for…
Montreal-born Sidney Altman awarded share of the Nobel Prize in Chemistry “for their discovery of catalytic properties of RNA”
In 1989, Montreal-born Sidney Altman won a share of the Nobel Prize in Chemistry “for their discovery of…
The human p53 gene was cloned
On Dec. 20, 1984, a team of scientists announced that a cDNA clone for human p53 cellular tumor…
Discovery that treatment with human recombinant interferon gamma blocks the growth of T. gondii published
On Feb. 8, 1984, Elmer R. Pfefferkorn published his discovery that treatment of human fibroblasts with human recombinant…
University of Washington scientists created first “transgenic mouse”
In 1982, Richard D. Palmiter at the University of Washington scientists created first “transgenic mouse” in collaboration with…
Serpata Therapeutics was founded, originally as AVI BioPharma
In 1980, Sarepta Therapeutics was founded originally as AVI BioPharma. Today, Sarepta is on an urgent mission: engineer…
The first human RNA virus (HTLV-I) was discovered by NCI’s Dr Robert C Gallo
In 1979, the first human RNA virus (HTLV-I) was discovered by the National Cancer Institute’s Dr. Robert C….
Joan Steitz discovered snRNPs
In 1979, Joan Steitz discovered snRNPs, RNA-protein complexes in the cell’s nucleus that perform a crucial step in…
Carl Woese, an American microbiologist, defined Archaea as a new domain
In 1978, Carl Woese, an American microbiologist defined Archaea as a new domain based upon genetic relationships that…
Virus particle structure was determined
In 1977, Harvard Medical School researcher Stephen C. Harrison first determined the structure of an intact virus particle,…
David Baltimore, Renato Dulbecco, and Howard Martin Temin awarded the 1975 Nobel Prize in Medicine
In 1975, Caltech President David Baltimore, former Caltech faculty member and Salk Institute researcher Renato Delbucco, and Caltech…
Stanford Medicine researchers discovered RNA priming of DNA synthesis
In 1971, Stanford Medicine researchers discovered RNA priming of DNA synthesis.
Carl Woese, an American microbiologist, suggested that RNA was the earliest source of genetic information
In 1967, Carl Woese, an American microbiologist, suggested that RNA was the earliest source of genetic information.
Hildegard Lamfrom was among the first to provide evidence of a messenger RNA, as well as evidence for the existence of polyribosomes
In 1958, Hildegard Lamfrom worked at Caltech, doing research in molecular biology. She was among the first to…