The FDA approved Gleevec for Five Rare, Life-Threatening Disorders
On Oct. 19, 2006, the U.S. Food and Drug Administration (FDA) approved the drug, Gleevec developed by Oregon…
Calistoga Pharmaceuticals was founded
In 2006, Calistoga Pharmaceuticals was founded as a Seattle-based spin-off from ICOS Corp. that was dedicated to developing…
Biotechnology | CDC | NIH | Oncology | Therapeutics | U.S. Congress
The Hematologic Cancer Research Investment and Education Act Signed into Law
On May 14, 2002, President George W. Bush signed the Hematologic Cancer Research Investment and Education Act of…
FDA approved Gleevec for gastrointestinal stromal tumors treatment
On Feb. 1, 2002, the U.S. Food and Drug Administration (FDA) approved the drug Gleevec, formerly known as…
$2.5 million award from Jeld-Wen Foundation endowed OHSU Chair in Leukemia Research for Brian Druker
On Nov. 7, 2001, the Oregon Health Sciences University Foundation (OHSU) announced that the Klamath Falls-based JELD-WEN Foundation…
The FDA approved Gleevec, developed by OHSU, for treatment of chronic myeloid leukemia
On May 10, 2001, the U.S. Food and Drug Administration (FDA) approved Gleevec, the world’s first targeted cancer…
The drug imatinib mesylate (Gleevec) was shown to be effective against chronic myelogenous leukemia
In 2001, the drug imatinib mesylate (Gleevec) was shown in a clinical trial to be effective against chronic…
Karmanos Institute and JP McCarthy Cord Stem Cell Bank founded
In 2001, The J.P. McCarthy Cord Stem Cell Bank at the Karmanos Cancer Institute was founded as a…
Researchers announced they had decoded human chromosomes 5, 16, and 19
In 2000, researchers from Lawrence Berkeley, Lawrence Livermore, and Los Alamos national laboratories at the Joint Genome Institute…
Cancer stem cells were first identified in acute myelogenous leukemia
In 1997, cancer stem cells were first identified in acute myelogenous leukemia. They will later be identified in…
Biotechnology | Diagnostics | Disease | Environmental | NIH | Oncology
Scientists found that occupational exposure to benzene is associated with increased risks of developing acute non-lymphocytic leukemia
In 1997, the National Cancer Institute (NCI) and Chinese scientists found that occupational exposure to benzene is associated…
Mouse model of promyelocytic leukemia was developed at Washington University – St Louis
In 1997, a mouse model of promyelocytic leukemia was developed by Washington University – St. Louis researcher Timothy…
Biotechnology | Disease | FDA | Oncology | Therapeutics
The FDA approved tretinoin, a differentiating agent related to vitamin A, for use in the treatment of acute promyelocytic leukemia
On Dec. 9, 1995, the U.S. Food and Drug Administration (FDA) approved tretinoin, a differentiating agent related to…
Infectious molecular clone of a human T-cell leukemia virus was developed at Washington University – St Louis
In 1994, Washington University – St. Louis reseacher Lee Ratern, MD and colleagues announced they had developed an…
The Oregon Cancer Center was founded at Oregon Health & Science University
In 1992, the Oregon Cancer Center, later known as the OHSU Cancer Institute, was founded at Oregon Health…
Gertrude B. Elion shared the Nobel Prize in Physiology or Medicine for the ‘discoveries of important principles for drug treatment’
In 1988, Gertrude B. Elion shared the Nobel Prize in Physiology or Medicine for the ‘discoveries of important…
Diagnostics | NIH | Oncology | Therapeutics
The Cold Spring Harbor Laboratory Cancer Center received NCI designation
In 1987, The Cold Spring Harbor Laboratory (CSHL) Cancer Center received National Cancer Institute (NCI) designation. CSHL researchers…
Biotechnology | FDA | Oncology | Therapeutics
Interferon became the first anticancer drug produced through biotechnology
On Jun. 5, 1986, the U.S. Food and Drug Administration (FDA) approved Hoffmann La Roche’s Interferon initially for…
NCI scientists isolated human T-cell lymphotrophic virus 1 (HTLV-1)
In 1980, National Cancer Institute (NCI) scientists from the Gallo group isolated human T-cell lymphotrophic virus 1 (HTLV-1)….
Interleukin-2 was discovered
In 1976, interleukin-2 was discovered and purified which allowed researchers to grow T-cells and study their immunology, which…
Dr. E. Donnall Thomas brought his pioneering work in bone marrow transplantation to the Fred Hutch
In 1975, Dr. E. Donnall Thomas, a pioneer in bone marrow transplantation, secured a permanent treatment home at…
The world’s first successful bone-marrow transplant completed at the University of Minnesota
In 1968, the world’s first successful bone-marrow transplant was completed at the University of Minnesota Hospital under the…
ER Squibb & Sons delved into cancer research, discovering and developing hydroxyurea for leukemia and advanced ovarian cancer
In 1967, E.R. Squibb & Sons delved into cancer research, discovering and developing hydroxyurea for leukemia and advanced…
St Jude patients were the first ALL patients to ever be successfully taken off therapy
In 1966, a group of St. Jude patients were the first acute lymphoblastic leukemia (ALL) patients to ever…
Stﾠ. Jude Children’s Hospital launched first major effort to understand progression of sickle cell disease
In 1966, a group of St. Jude patients were the first acute lymphoblastic leukemia (ALL) patients to ever…
The Acute Leukemia Task Force held its first meeting
On May 7, 1962, the Acute Leukemia Task Force held its first meeting. It focused the combined efforts…
The CDC performed the first Epidemic Intelligence Service investigation for chronic disease
In 1962, the U.S. Centers for Disease Control and Prevention (CDC) performed the first Epidemic Intelligence Service (EIS)…
Chromosome abnormalities were associated with leukemias
In 1960, chromosome abnormalities were associated with leukemias.
NCI scientists pioneer the use of combination chemotherapy
In 1958, NCI scientists pioneer the use of combination chemotherapy. Partial and complete remissions, as well as prolonged…
The FDA approved methotrexate, an antimetabolite derived from folic acid, and 6-mercaptopurine as anticancer drugs
On Dec. 7, 1953, the U.S. Food and Drug Administration (FDA) approved Dava Pharmaceuticals’ methotrexate oral tablet, an…