On May 11, 2023, the National Institutes of Health launching a new program, the Common Fundﾒs Somatic Mosaicism Across Human Tissues (SMaHT) Network, that aims to transform our knowledge of how much genetic variation there is in the cells and tissues throughout our bodies. Somatic mosaicism can alter how cells function and may influence human development, disease, aging, and other physiological measures across the lifespan.

The SMaHT Network, with awards totaling $140 million dollars over five years, pending availability of funds, seeks to discover and catalog the breadth of somatic mosaicism in human tissues.