On Jul. 25, 2023, U.S. National Science Foundation-supported research, led by Joshua Rosenthal of the Marine Biological Laboratory and colleagues, reported that octopuses and their close relatives elegantly adjust to environmental challenges by tinkering with their RNA ﾗ an intermediary molecule that conveys DNA’s directions. In a study appearing in the journal Cell, the researchers document an enormous uptick in RNA editing when octopuses, squid and cuttlefish, known as coleoid cephalopods, acclimate to cold water.