On Feb. 22, 2023, the Centers for Disease Control and Prevention (CDC) reported that the 2022-2023 flu vaccines reduced the risk of influenza A-related hospitalization among children by nearly three quarters and among adults by nearly half.

According to data from the Vaccine Surveillance Network (NVSN), VE against the predominant H3N2 viruses was 45% among children, which is higher than seen previously for this virus.