On May 18, 2022, scientists at the Centers for Disease Control and Prevention (CDC) announced that they were collaborating with the Massachusetts Department of Public Health to investigate a case of monkeypox in a Massachusetts resident who had recently traveled to Canada by private transportation.

CDC was also tracking multiple clusters of mpox that were reported within the past two weeks in several countries that don’t normally report mpox, including Portugal, Spain, and the United Kingdom. It’s not clear how people in those clusters were exposed to mpox but cases include individuals who self-identify as men who have sex with men.  CDC was urging healthcare providers in the U.S. to be alert for patients who have rash illnesses consistent with monkeypox, regardless of whether they have travel or specific risk factors for mpox.