On Oct. 30, 2021, Penn Medicine officially opened the doors of its 1.5 million-square-foot future-ready Pavilion as clinical staff transported 310 patients from the Hospital of the University of Pennsylvania into the new facility.

The 17-story building on Penn Medicineﾒs West Philadelphia campus, which houses 504 private patient rooms and 47 operating rooms, was an expanded footprint of HUP. The Pavilion is poised to serve as a launch pad for Penn Medicine’s next generation of pioneering advances in patient care, according to Kevin Mahoney, CEO of the University of Pennsylvania Health System.

The $1.6 billion facility—the culmination of years of planning and construction—represents the latest piece of a connected medical campus, which includes HUP, the Perelman Center for Advanced Medicine for outpatient care, and the Smilow Center for Translational Research. It is the largest capital project in the University of Pennsylvania’s history, the largest hospital project in the Philadelphia region, and one of the largest in the United States.