
Analysis of COVID-19 genomes revealed large numbers of introductions to the UK in March, 2020
On May 22, 2020, data reports, published by the COVID-19 Genomics UK Consortium (COG-UK), showed the value in mapping COVID-19 lineages across the UK to understand how the virus was spreading at national, regional and local levels. Approximately 40 lineages of the SARS-CoV-2 virus had been recorded circulating in the UK, some of which had already gone extinct while others thrive.
Previously, the different lineages of the single strain of the virus entered the UK through multiple importations from around the globe, including European countries such as Spain, Italy and France.
Now, fewer international lineages remain in the UK and new cases of COVID-19 arise from local spread rather than importation from other countries. The data reports, published by the COVID-19 Genomics UK Consortium (COG-UK), show the value in mapping COVID-19 lineages across the UK to understand how the virus is spreading at national, regional and local levels.
As of 22 May, more than 20,000 viral genomes from positive COVID-19 tests have been sequenced in the UK, which is the largest number of COVID-19 genomes sequenced by any single country affected by the pandemic.
These genome sequences are being generated and utilised by researchers within COG-UK to identify different lineages* of the virus circulating in the UK. Despite recent reports, this volume of sequencing confirms the all COVID-19 cases in the UK share a recent common ancestor from China; all cases are closely related. The lineages identified highlight small changes to the virus that enable monitoring and tracking over time, but do not signal the emergence of new strains at this point in the outbreak.
These data will aid the UK government in understanding patterns of spread in the UK to help focus different interventions in particular areas of the UK to control the spread of the virus and ultimately save lives.
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Source: Wellcome Trust Sanger Institute
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