On May 19, 2023, HealthPartners Institute researchers have published new data in JAMA Network Open that shows monovalent COVID-19 booster vaccinations administered in early pregnancy (before 20 weeksﾒ gestation) were not associated with miscarriage.

The researchers analyzed data from more than 100,000 pregnancies between six and 19 weeksﾒ gestation from eight large health systems participating in the Vaccine Safety Datalink (VSD). The data was collected between Nov. 1, 2021, and June 12, 2022. Researchers found, using a 28- or 42-day window, that receipt of a booster vaccination was not associated with miscarriage.