FDA approved gilteritinib, a targeted drug for leukemia tested at UPenn

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On Nov. 28, 2018, The U.S. Food and Drug Administration (FDA) announced it had approved the first ever inhibitor drug specifically approved for treating patients with relapsed or refractory acute myeloid leukemia (AML) with a mutation in the Fms-like tyrosine kinase 3 (FLT3) gene.

Patients with these mutations who have relapsed or refractory AML have very low response rates to chemotherapy at the time of relapse and their survival is poor as a result.

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Source: Penn Medicine
Credit: Photo: Microscopy of acute leukemia in bone_marrow, courtesy American Society of Hematology.