On Sept. 20, 2017, resarchers at deCODE genetics use whole-genome data from 14,000 people from across the population of Iceland, including 1500 sets of parents and children, to provide the most detailed portrait to date of how sequence diversity in humans is the result of an evolving interaction between sex, age, mutation type and location in the genome.

‘The study, published in Nature, showed that in about 10% of the genome, the de novo mutations coming from the mother equal in number the ones coming from the father. Most of the maternally derived de novo mutations in these regions are C-to-G (C>G) mutations and are rooted in flaws in the repair of double-strand breaks.