On Jul. 29, 1998, the diphtheria and tetanus toxoids and acellular pertussis vaccine adsorbed (Certiva by North American Vaccine) was licensed for primary and booster immunization of infants and children (except as a 5th dose in children who have previously received 4 doses of DTaP).

Vaccine doses should be administered at ages 2, 4, 6, and 15-20 months. Data were insufficient to evaluate the use of Certiva™ as a fifth dose among children aged 4-6 years who had received Certiva™ for the previous four doses.