On Feb. 19, 2024, the National Institutes of Health (NIH) announced that researchers had discovered more than 275 million previously unreported genetic variants, identified from data shared by nearly 250,000 participants of the NIH’s All of Us Research Program.

Half of the genomic data are from participants of non-European genetic ancestry. The unexplored cache of variants provides researchers new pathways to better understand the genetic influences on health and disease, especially in communities who have been left out of research in the past. The findings are detailed in (link is external)Nature(link is external), along with three other articles in Nature journals.